Mukutsvaga kwepasi, masayendisiti akaita kufambira mberi kukuru mukunzwisisa basa re superoxide dismutase (SOD) mukuchengetedza hutano hweserura.SODiyo enzyme yakakosha inoita basa rakakosha mukudzivirira maseru kubva kune oxidative kusagadzikana nekumisa anokuvadza emahara radicals. Kuwanikwa uku kune mukana wekushandura marapirwo ezvirwere zvakasiyana siyana zvine chekuita nekukuvara kweoxidative, senge cancer, neurodegenerative disorders, uye mamiriro ane chekuita nekuchembera.
KuongororaeffectyeSuperoxide Dismutase (SOD) :
Vatsvakurudzi vagara vachiziva kukosha kweSODmuhutano hwemaserura, asi nzira chaidzo dzaanoshanda nadzo dzakaramba dzisinganzwisisike. Zvakadaro, ongororo ichangoburwa yakabudiswa mupepanhau Nature Communications yakapa chiedza chitsva panyaya iyi. Chidzidzo chacho chakaratidza izvozvoSODkwete chete scavenges inokuvadza superoxide radicals asi zvakare inogadzirisa kutaura kwemajini anosanganisirwa mumaserura ekudzivirira nzira, nekudaro ichiwedzera kugona kwesero kutsungirira oxidative kusagadzikana.
Zvinorehwa nekuwanikwa uku zvinosvika kure, sezvo zvichivhura mikana mitsva yekugadzira marapirwo anonangwa emamiriro ane chekuita nekukuvara kweoxidative. Nekuwana nzwisiso yakadzama yekuti seiSODinoshanda pachikamu chemolecular, vesainzi vanogona ikozvino kuongorora nzira itsva dzekugadzirisa chiitiko chayo uye nekugona kudzikisira kukanganiswa kweoxidative kushushikana kweserura. Izvi zvinogona kutungamira mukuvandudzwa kwemishonga inoshanda yezvirwere zvakasiyana siyana, zvichipa tariro kumamiriyoni evarwere pasi rese.
Uyezve, zvakawanikwa zvechidzidzo zvine mukana wekuzivisa kuvandudzwa kwemaitiro ekudzivirira kuchengetedza hutano hweserura uye kunonoka kuchembera. Nekushandisa zvinodzivirira zveSOD, vatsvakurudzi vanogona kukwanisa kugadziridza kupindira kunogona kubatsira vanhu kuchengetedza zvakakwana masero ekushanda sezvavanokura, kuderedza dambudziko rezvirwere zvinokonzerwa nezera uye kukurudzira hutano hwakakwana.
Mukupedzisa, kubudirira kuchangobva kuitika mukunzwisisa basa reSOD muhutano hwemaserura inomiririra kufambira mberi kwakakosha mumunda wekutsvagisa biomedical. Kuburikidza nekukanyura mashandiro akaomararaSOD inodzivirira masero kubva mukukuvadzwa kweoxidative, masayendisiti akagadzira nzira yekuvandudzwa kwemaitiro matsva ekurapa uye kupindira kwekudzivirira. Kuwanikwa uku kune vimbiso huru yekuvandudza marapirwo uye manejimendi ezvirwere zvine chekuita neoxidative kusagadzikana, zvichipa tariro yeramangwana rine hutano kune vanhu pasirese.
Nguva yekutumira: Jul-25-2024
