ChiiCoenzyme Q10?
Coenzyme Q10 (Coenzyme Q10, CoQ10), inozivikanwawo seUbiquinone (UQ) uye Coenzyme Q (CoQ), icoenzyme iripo mune zvese eukaryotic zvipenyu zvinoita aerobic kufema. Iine benzoquinone mafuta-soluble compound ine chimiro chakafanana nevhitamini K. Q inomiririra boka requinone, uye 10 inomiririra nhamba ye isoprene yakanamatira kumuswe wayo. Inonyanya kuumbwa mukati me membrane ye mitochondria, uye chikamu chiduku chinogonawo kuwanikwa kuburikidza nekudya, zvakadai semombe, mazai, hove dzine mafuta, nzungu, maranjisi, broccoli nemimwe michero nemiriwo.
Coenzyme Q10 yakagovaniswa zvakanyanya mumuviri wemunhu uye inowanikwa mune dzakasiyana nhengo, matishu, subcellular zvikamu uye plasma, asi zvirimo zvinosiyana zvakanyanya. Huremu hwekusangana hwakakwira mumatishu uye nhengo dzakaita sechiropa, moyo, itsvo uye pancreas. Basa guru nderekufambisa masero evanhu kuti abudise simba. Coenzyme Q10 inonyanya kubatanidzwa mumitochondrial oxidative phosphorylation uye ATP kugadzirwa, inogadzirisa sero redox nharaunda, inotakura maerekitironi akaderedzwa kupinda muvhesi kana kubuda musero panguva ye electron membrane penetration process, uye inotora chikamu mukuumbwa kwe proton gradient ye membrane yemukati uye membrane yeplasma. Inogona kukurumidzira kuvandudzwa kwesero uye kukurudzira kushanda kwesero, nekudaro ichikurudzira zvakanyanya kugona kwemaseru kutora zvinovaka muviri. Kuwedzera coenzyme Q10 zvinongedzo kune zvigadzirwa zvekuchengetedza ganda zvinogona kunyatsobatsira maseru eganda kushingaira kutora zvimwe zvinovaka muviri muzvigadzirwa zvekuchengetedza ganda, uye zvine hutano-kuchengetedza mhedzisiro sekumhanyisa metabolism uye kuderedza kuchembera.
Sechigadzirwa chehutano, coenzyme Q10 ine mabasa ekuchengetedza moyo, kuwedzera simba, nekuvandudza kusadzivirirwa. Inokodzera vatambi, vashandi vepfungwa vane simba, uye kudzikamisa uye kupora kwevarwere vane chirwere chemoyo, chirwere cheshuga, nezvimwe.
Zvenyama Uye Zvemakemikari Zvivakwa zveCoenzyme Q10
Kuonekwa kweCoenzyme Q10:Yellow kana orenji-yellow crystalline powder; isina kunhuwa uye isina kunaka; nyore kuora nechiedza.
Ruvara:orenji yakareruka kusvika kuruvara rweorenji
Melting point:49-51℃
Boiling point:715.32℃
Density:0.9145 g/cm3
Refractive index:1.4760
Mamiriro ekuchengetera:Inogona kuchengetwa pakamuri tembiricha kwenguva pfupi, zviri nani pa -20 ℃ kuchengetedza kwenguva refu.
Solubility:Zviri nyore soluble mu chloroform.
Sensitivity:photosensitivity
Kugadzikana:Yakagadzikana, asi inonzwa kuchiedza kana kupisa, isingaenderane nemaoxidants akasimba.
Distribution OfCoenzyme Q10Mumuviri Wemunhu
Coenzyme Q10 inowanikwa zvakanyanya mumasero membranes, kunyanya mumitochondrial membranes, uye inonyanya kugoverwa mumoyo, mapapu, chiropa, itsvo, spleen, pancreas uye adrenal glands. Iyo yakazara muviri yemukati yeCoenzyme Q10 inongova 500 ~ 1500mg, asi inoita basa rakakosha. Coenzyme Q10 yakakwira zvakanyanya mumoyo, itsvo, chiropa uye tsandanyama. Panguva imwecheteyo, 95% yeCoenzyme Q10 mumuviri wemunhu iripo muchimiro cheubiquinol (yakaderedzwa Ubiquinol), asi uropi nemapapu hazvibatanidzwe. Zvinofungidzirwa kuti zvinogona kunge zvichikonzerwa nekunyanya kushushikana kweiyo oxidative mumatishu maviri aya, ayo anoisa ubiquinol kuita oxidized ubiquinone (oxidized Ubiquinone).
Nekuderera kwezera, zvirimo zveCoenzyme Q10 mumuviri wemunhu zvichadzikira zvishoma nezvishoma. Kutora makore makumi maviri semutsetse wakajairwa, pazera re80, iyo yepanyama attenuation yeCoenzyme Q10 munzvimbo dzakasiyana dzemuviri wemunhu ndeye: chiropa: 83.0%; itsvo: 65.3%; mapapu: 51.7%; mwoyo: 42.9%. Nokudaro, zvinowanzogamuchirwa kuti mwoyo ndiyo nhengo inonyanya kuda coenzyme Q10 supplementation, kana kuti vazhinji vakwegura mwoyo kusagadzikana kunobva mukushayikwa kwecoenzyme Q10.
Ndezvipi ZvakanakiraCoenzyme Q10?
Mamwe emabhenefiti anogona kuitika eCoQ10 anosanganisira:
1. Hutano hwemoyo hwakavandudzwa:CoQ10 yakaratidzwa kutsigira hutano hwemoyo nekubatsira kuvandudza kugadzirwa kwesimba mumhasuru yemoyo, pamwe nekuita se antioxidant kudzivirira kubva mukushushikana kweiyo oxidative.
2. Kuwedzera kugadzirwa kwesimba:CoQ10 inobatanidzwa mukugadzirwa kweadenosine triphosphate (ATP), inova ndiyo yekutanga simba remasero. Kuwedzera neCoQ10 kunogona kubatsira kuwedzera mazinga esimba, kunyanya kune vanhu vane yakaderera CoQ10 mazinga.
3. Antioxidant properties:CoQ10 inobatsira kudzikamisa mahara radicals uye kuderedza oxidative kukuvara mumuviri, izvo zvinogona kubatsira kudzivirira kubva kune dzakasiyana zvirwere zvisingaperi uye kutsigira hutano hwese.
4. Zvinogona kurwisa kuchembera mhedzisiro:Imwe tsvagiridzo inoratidza kuti CoQ10 inogona kunge iine anti-kuchembera mhedzisiro nekuda kwekugona kwayo kuchengetedza maseru kubva mukukuvadzwa kweoxidative uye kutsigira kugadzirwa kwesimba remagetsi.
5.Kutsigira vashandisi ve statin:Mishonga yeStatin, iyo inowanzonyorerwa kuderedza cholesterol, inogona kuderedza CoQ10 mazinga mumuviri. Kuwedzera neCoQ10 kunogona kubatsira kudzikisira mhedzisiro yekushandisa statin, sekurwadziwa kwemhasuru uye kushaya simba.
Chii chinonzi Applications OfCoenzyme Q10?
Coenzyme Q10 (CoQ10) ine akati wandei maapplication nekuda kwekugona kwayo hutano mabhenefiti. Zvimwe zvekushandisa zvakakosha zveCoQ10 zvinosanganisira:
1. Utano hwemwoyo:CoQ10 inowanzoshandiswa kutsigira hutano hwemwoyo, kunyanya kune vanhu vane mwoyo kukundikana, high blood pressure, kana mamwe mamiriro emwoyo. Inogona kubatsira kuvandudza kugadzirwa kwesimba mukati memhasuru yemoyo uye kuita se antioxidant kudzivirira kubva kune oxidative kusagadzikana.
2. Mitochondrial kusagadzikana:CoQ10 dzimwe nguva inoshandiswa sekuwedzera kune vanhu vane mitochondrial kusagadzikana, sezvo ichiita basa rakakosha mukugadzira simba mukati memitochondria.
3. Statin-induced myopathy:CoQ10 supplementation dzimwe nguva inokurudzirwa kune vanhu vanotora statin mishonga kuderedza cholesterol, sezvo statins inogona kupedza CoQ10 mazinga mumuviri. Kuwedzera neCoQ10 kunogona kubatsira kuderedza marwadzo emhasuru uye kushaya simba kwakabatana nekushandiswa kwe statin.
4. Anti-kuchembera uye hutano hweganda:CoQ10 inoshandiswa mune zvimwe zvigadzirwa zve skincare nekuda kweiyo antioxidant zvimiro, izvo zvinogona kubatsira kuchengetedza ganda kubva mukukuvadzwa kweoxidative uye kutsigira hutano hwese hweganda.
5. Kudzivirira Migraine:Imwe tsvakurudzo inoratidza kuti CoQ10 supplementation inogona kubatsira kuderedza kuwanda uye kuoma kwemigraines, kunyange zvazvo zvidzidzo zvakawanda zvichidiwa kusimbisa kushanda kwayo kwechinangwa ichi.
6. Kudzidzira kuita:CoQ10 inogona kubatsira kuvandudza kurovedza muviri uye kupora nekutsigira kugadzirwa kwesimba uye kuderedza oxidative kusagadzikana mumamhasuru.
Coenzyme q10 Zvemukati MuZvokudya Zvakafanana
| Coenzyme Q10 yemukati pakg yechikafu (mg) | |||
| Zvokudya | CoQ10 zvirimo | Zvokudya | CoQ10 zvirimo |
| Sardines | 33.6 | Chibage | 6.9 |
| Saury | 26.8 | Brown mupunga | 5.4 |
| Mwoyo wenguruve | 25.6 | Sipinachi | 5.1 |
| Nguruve chiropa | 25.1 | Miriwo yegirini | 3.2 |
| Hove nhema | 25.1 | Rapeseed | 2.7 |
| Nguruve chiuno | 24.7 | Makarotsi | 2.6 |
| Salmon | 22.5 | Lettuce | 2.5 |
| Mackerel | 21.8 | Madomasi | 2.5 |
| Beef | 21.2 | Kiwifruit | 2.4 |
| Nguruve | 16.1 | Celery | 2.3 |
| Nzungu | 11.3 | Mbatatisi dzinotapira | 2.3 |
| Broccoli | 10.8 | Oranges | 2.3 |
| Cherries | 10.7 | Eggplant | 2.3 |
| Bhari | 10.6 | Peas | 2.0 |
| Soya beans | 7.3 | Lotus mudzi | 1.3 |
Inoenderana Mibvunzo Unogona Kufarira:
Ndeapi Maside Effects ECoenzyme Q10?
Coenzyme Q10 (CoQ10) inowanzoonekwa seyakachengeteka kune vanhu vazhinji kana ichitorwa mumitengo yakakodzera. Zvisinei, vamwe vanhu vanogona kuwana mild side effects. Izvi zvinogona kusanganisira:
1. Nyaya dzekugaya:Vamwe vanhu vanogona kuwana zvinyoro-nyoro zviratidzo zvemudumbu senge kusvotwa, manyoka, kana kushushikana mudumbu kana vachitora CoQ10 supplements.
2. Kusarara:Mune zvimwe zviitiko, CoQ10 supplementation yakabatanidzwa nekunetseka kurara kana kushaya hope, kunyanya kana ichitorwa manheru.
3. Kusawirirana nevamwe:Kunyangwe zvisingawanzo, vamwe vanhu vanogona kunge vasingawirirani neCoQ10 uye vanogona kuona zviratidzo zvakaita semapundu, kukwenya, kana kunetseka kufema.
4. Kudyidzana nemishonga:CoQ10 inogona kudyidzana nemimwe mishonga, yakadai seropa rakapfava uye mishonga yeBP. Zvakakosha kubvunza nyanzvi yezvehutano usati watora CoQ10 kana uri pamishonga chero ipi zvayo.
Izvo zvakakosha kuti uzive kuti ruzhinji rwevanhu vanoshivirira CoQ10 zvakanaka, uye zvakakomba mhedzisiro hazviwanzo. Nekudaro, sekunge chero chekuwedzera, zvinokurudzirwa kubvunzana nemupi wehutano usati watanga CoQ10 yekuwedzera, kunyanya kana uine chero mamiriro ehutano ari pasi pehutano kana uri kutora mishonga.
Iwe unofanirwa kutora CoQ10 mazuva ese?
Sarudzo yekutora Coenzyme Q10 (CoQ10) zuva nezuva inofanira kubva pane zvinodiwa zvehutano hwemunhu uye kuraira kwenyanzvi yehutano. CoQ10 inogadzirwa mumuviri uye inowanikwawo kuburikidza nezvimwe zvekudya. Nekudaro, sekukura kwevanhu kana mune mamwe mamiriro ehutano, kugadzirwa kwemuviri kweCoQ10 kunogona kudzikira.
Kune vanhu vari kufunga nezveCoQ10 supplementation, zvakakosha kubvunzana nemupi wehutano kuti vaone muyero wakakodzera uye frequency zvichienderana nemamiriro ehutano ega, kushomeka kunogona kuitika, uye chero mamiriro ehutano aripo. Mune zvimwe zviitiko, nyanzvi yehutano inogona kukurudzira kutora CoQ10 zuva rega rega, asi mune mamwe mamiriro ezvinhu, chirongwa chedosing chakasiyana chingave chakakodzera.
Ndiani asingakwanise kutora CoQ10?
Vamwe vanhu vanofanirwa kungwarira kana kudzivirira kutora Coenzyme Q10 (CoQ10) vasina kubvunza nyanzvi yehutano. Izvi zvinogona kusanganisira:
1. Vakadzi vane pamuviri kana vanoyamwisa:Nepo CoQ10 ichiwanzoonekwa seyakachengeteka, pane tsvakiridzo shoma pamusoro pekuchengetedza kwayo panguva yekuzvitakura nekuyamwisa. Nokudaro, zvinokurudzirwa kuti vakadzi vane pamuviri kana vanoyamwisa vatange vaonana nemupi wehutano vasati vashandisa CoQ10.
2. Vanhu vari kutora mishonga inoderedza ropa:CoQ10 inogona kudyidzana nemishonga yeanticoagulant yakadai sewarfarin (Coumadin) kana antiplatelet zvinodhaka senge aspirin. Zvakakosha kuti vanhu vari pamishonga iyi vatsvage mazano ekurapa vasati vatanga CoQ10 supplementation.
3. Vanhu vane hutano huripo:Vanhu vane zvimwe zvirwere, zvakadai sechirwere chechiropa, chirwere cheitsvo, kana chirwere cheshuga, vanofanira kuonana nemupi wehutano vasati vatora CoQ10, sezvo inogona kupindirana nemishonga inoshandiswa kugadzirisa mamiriro aya.
4. Avo vane allergies vanozivikanwa:Vanhu vanoziva allergies kuCoQ10 kana makomisheni ane hukama vanofanirwa kudzivirira kushandiswa kwayo.
Ndezvipi zviratidzo zvekudaCoQ10?
Zviratidzo zvekuda Coenzyme Q10 (CoQ10) yekuwedzera haisi nguva dzose yakatwasuka, sezvo inogona kuve yakapusa uye inogona kupindirana nezviratidzo zvehutano hwakasiyana. Nekudaro, zvimwe zviratidzo zvinogona kuratidza kushomeka muCoQ10 zvinosanganisira:
1. Kuneta uye kuderera kwesimba mazinga:CoQ10 inoita basa rakakosha mukugadzirwa kwesimba remagetsi. Naizvozvo, kuramba kuneta uye kuderera kwesimba mazinga anogona kuve chiratidzo chekushomeka kweCoQ10.
2. Kushaya simba kwetsandanyama uye kurwadziwa:Kushaikwa kweCoQ10 kunogona kuita kuti tsandanyama kushaya simba, kurwadziwa, uye cramps, sezvo ichibatanidzwa mukugadzira simba mukati memhasuru maseru.
3. High blood pressure:Imwe tsvakurudzo inoratidza kuti yakaderera mazinga eCoQ10 angave akabatanidzwa nepamusoro-soro yeropa, uye kuwedzera kunogona kubatsira kutsigira utano hwemwoyo.
4. Chirwere chemazino:CoQ10 inobatanidzwa mukuchengetedza hutano hwemagum tishu, uye kushomeka kunogona kukonzera chirwere chegum kana matambudziko e periodontal.
5. Migraine misoro:Zvimwe zvidzidzo zvakaratidza kuti CoQ10 supplementation inogona kubatsira kuderedza kuwanda uye kuoma kwemigraines, zvichiratidza kuti pasi CoQ10 mazinga anogona kunge ari chinhu chinokonzera migraines mune vamwe vanhu.
Zvinotora nguva yakareba sei kuti uone mabhenefiti?
Iyo nguva inotora kuona mabhenefiti eCoenzyme Q10 (CoQ10) inogona kusiyanisa zvichienderana nehutano hwemunhu, mamiriro ehutano chaiwo ari kutariswa, uye dosage yeCoQ10 iri kushandiswa. Mune zvimwe zviitiko, vanhu vanogona kuwana mabhenefiti nekukurumidza, nepo mune mamwe mamiriro, zvinogona kutora nguva yakareba kuti uone chero mhedzisiro.
Kune mamwe mamiriro akadai sekutadza kwemoyo kana kukwira kweropa, zvinogona kutora mavhiki akati wandei kusvika kumwedzi yekuenderana kweCoQ10 yekuwedzera kuona kuvandudzwa kwezviratidzo. Nekune rimwe divi, vanhu vanotora CoQ10 yerutsigiro rwesimba rakawanda kana se antioxidant vanogona kuona mabhenefiti akadai sekuwedzera masimba esimba kana kuvandudzwa kwese kugara mukati menguva pfupi, pamwe mukati memavhiki mashoma.
Nguva yekutumira: Sep-19-2024
