ChiiSulforaphane?
Sulforaphane is isothiocyanate, iyo inowanikwa ne hydrolysis ye glucosinolate ne myrosinase enzyme muzvirimwa. Iyo yakawanda mumiti yecruciferous senge broccoli, kale, uye kuchamhembe kwekaroti. Iyo yakajairika antioxidant uye inonyanya kushanda chirimwa chinoshanda muanti-cancer mhedzisiro inowanikwa mumiriwo.
Zvenyama Uye Kemikari Zvivakwa zveSulforaphane
Zvinhu zvemuviri
1. Chitarisiko:
-Sulforaphane inowanzoita isina ruvara kune yakachenuruka yero crystalline yakasimba kana ine mafuta mvura.
2. Solubility:
-Mvura Solubility: Sulforaphane ine yakaderera solubility mumvura.
-Solubility muorganic solvents: Sulforaphane ine yakanaka solubility muorganic solvents senge ethanol, methanol uye dichloromethane.
3. Kunyungudika:
- Nzvimbo yekunyungudika yeSulforaphane inotangira pa60-70°C.
4. Boiling Point:
- Nzvimbo yekubikira yeSulforaphane inenge 142 ° C (pakumanikidza kwe0.05 mmHg).
5. Density:
- Kuwanda kweSulforaphane kunosvika 1.3 g/cm³.
Chemical Properties
1. Kuumbwa Kwemakemikari:
- Zita remakemikari yeSulforaphane ndeye 1-isothiocyanate-4-methylsulfonylbutane, maitiro ayo emakemikari ndeyeC6H11NOS2, uye uremu hwayo hwema molecular 177.29 g / mol.
- Chimiro chayo chine isothiocyanate (-N = C = S) boka uye methylsulfonyl (-SO2CH3) boka.
2. Kugadzikana:
-Sulforaphane yakagadzikana pasi pekusarerekera uye isina kusimba acidic mamiriro, asi nyore kuparara pasi pesimba rakasimba uye alkaline mamiriro.
-Kunzwa kuchiedza nekupisa, kuratidzwa kwenguva refu kune mwenje uye tembiricha yakakwira inogona kukonzera kuderera kwayo.
3. Reactivity:
-Sulforaphane ine yakakwira makemikari reactivity uye inogona kuita neakasiyana siyana biological mamorekuru.
-Iyo isothiocyanate boka rinogona kusanganisa pamwe ne sulfhydryl (-SH) uye amino (-NH2) mapoka kuti aumbe yakagadzikana yekuwedzera zvigadzirwa.
4. Antioxidant:
-Sulforaphane ine simba antioxidant zvivakwa, inokwanisa kudzikamisa mahara radicals uye kuderedza oxidative kusagadzikana kukuvara kumasero.
5. Biological Activity:
- Sulforaphane ine zvinhu zvakasiyana-siyana zvehupenyu, kusanganisira anti-cancer, anti-inflammatory, detoxification uye neuroprotection.
KwakabvaSulforaphane
Main sources
1. Broccoli:
- Broccoli Inomera: Broccoli nhungirwa ndeimwe yepamusoro sosi yeSulforaphane. Tsvagiridzo inoratidza kuti iyo Sulforaphane yemukati mune broccoli inomera yakapetwa kakapetwa kakapetwa kupfuura iyo mune yakakura broccoli.
- Ripe Broccoli: Kunyangwe iyo Sulforaphane yemukati isiri yakakwira senge broccoli inomera, yakakura broccoli ichiri yakakosha sosi yeSulforaphane.
2. Korifurawa:
- Koliflower zvakare muriwo wecruciferous wakapfuma musulforaphane, kunyanya mabukira ayo madiki.
3. Kabheji:
- Kabichi, kusanganisira tsvuku uye girinhi makabheji, ine mamwe ehuwandu hweSulforaphane.
4. Mustard Greens:
-Masitadhi magidhi zvakare inzvimbo yakanaka yeSulforaphane, kunyanya mapfumvu avo madiki.
5. Kare:
- Kale imiriwo-dense cruciferous yemiriwo ine Sulforaphane.
6. Radhishi:
- Radish nemabukira ayo anewo Sulforaphane.
7. Mimwe miriwo yecruciferous:
- Mimwe miriwo yecruciferous yakadai seBrussels Sprouts, Turnip, Chinese Kale, nezvimwewo inewo huwandu hweSulforaphane.
Sulforaphane generation process
Sulforaphane haisipo zvakananga mumiriwo iyi, asi mune yayo yekutanga fomu, glucose isothiocyanate (glucoraphanin). Kana miriwo iyi yachekwa, kutsengwa kana kuputsika, madziro esero anotsemuka, achiburitsa enzyme inonzi myrosinase. Iyi enzyme inoshandura glucose isothiocyanate kuita Sulforaphane.
Kurudziro yekuwedzera yako Sulforaphane kudya
1.Zvinodyiwa zvinomera: Sarudza kudya zvinomera zvikamu zvakadai se broccoli inomera nokuti ine yakakwirira yeSulforaphane content.
2. Kubika Kwechiedza: Dzivisa kunyanyisa, sezvo kutonhora kwakanyanya kuchaparadza glucosinosidase uye kuderedza kugadzirwa kweSulforaphane. Kupisa zvinyoro inzira iri nani yekubika.
3. Zvokudya zvakasvibirira: Zvokudya zvakasvibirira zvemiti yecruciferous zvinogona kuchengetedza glucosinolate enzyme kusvika pamwero mukuru uye kukurudzira kugadzirwa kweSulforaphane.
4. Wedzera masardard: Kana iwe uchida kubika, unogona kuwedzera imwe yemasitadhi usati wadya, nokuti masitadhi ine glucosinolates, iyo inogona kubatsira kubudisa Sulforaphane.
Ndezvipi ZvakanakiraSulforaphane?
Sulforaphane ine hutano hwakasiyana siyana mabhenefiti, heano makuru mhedzisiro uye mabhenefiti eSulforaphane:
1. Antioxidant:
-Neutralizing Yemahara Radicals: Sulforaphane ine yakasimba antioxidant zvivakwa izvo zvinoderedza mahara radicals uye kuderedza kukuvadzwa kwemaseru kunokonzerwa neoxidative kusagadzikana.
- Activate antioxidant enzymes: Wedzera iyo antioxidant simba remasero nekuita iyo antioxidant enzyme system mumuviri, senge glutathione peroxidase uye superoxide dismutase.
2. Anti-gomarara:
Inhibit cancer maseru kukura: Sulforaphane inogona kutadzisa kukura uye kuwanda kweakasiyana maseru egomarara, kusanganisira kenza yemazamu, kenza yeprostate, uye colon cancer.
- Kurudzira apoptosis: Deredza chiyero chekupona kwekenza maseru nekuita apoptosis (yakarongwa sero kufa) kwekenza maseru.
- Inhibit tumor angiogenesis: Dzivirira kuumbwa kwetsinga itsva dzeropa mumamota, kudzikisira kupihwa kwechikafu kumamota, nekudaro ichitadzisa bundu kukura.
3. Anti-kuzvimba:
- Deredzai Inflammatory Response: Sulforaphane ine anti-inflammatory properties, iyo inogona kudzivisa kusunungurwa kwevamiririri vanopisa uye kuderedza mhinduro dzekuputika.
- Chengetedza Tissue: Inodzivirira matishu kubva mukukuvadzwa kunokonzerwa nekuzvimba nekuderedza kuzvimba.
4. Detoxification:
- Kurudzira kugadzirwa kwe detoxification enzymes: Sulforaphane inogona kumisa iyo detoxification enzyme system mumuviri, senge glutathione-S-transferase, kubatsira kubvisa zvinokuvadza uye chepfu kubva mumuviri.
-Kuvandudza kushanda kwechiropa: Chengetedza hutano hwechiropa nekusimudzira basa rekubvisa chetoxification.
5. Neuroprotection:
- Chengetedza Nerve Cells: Sulforaphane ine neuroprotective mhedzisiro uye inokwanisa kuchengetedza masero etsinga kubva mukukuvadzwa neoxidative kusagadzikana uye kuzvimba.
- Inodzivirira Neurodegenerative Zvirwere: Tsvagiridzo inoratidza kuti Sulforaphane inogona kubatsira kudzivirira uye kunonoka kufambira mberi kwezvirwere zveurourodegenerative senge chirwere cheAlzheimer uye chirwere cheParkinson.
6. Cardiovascular Health:
-DERERERA KUDIKIRWA KWEROPA: Sulforaphane inobatsira kudzikisa BP uye kuvandudza hutano hwemoyo.
- Inoderedza arteriosclerosis: Kuburikidza neantioxidant uye anti-kuzvimba mhedzisiro, Sulforaphane inogona kuderedza njodzi yearteriosclerosis uye kudzivirira iyo yemwoyo system.
7. Antibacterial uye Antiviral:
- Pathogen Inhibition: Sulforaphane ine antibacterial uye antiviral properties iyo inodzivisa kukura uye kubereka kwemarudzi akasiyana-siyana ehutachiona.
- Kuwedzera immune function: Kuvandudza kugona kwemuviri kurwisa hutachiona nekusimudzira basa rekudzivirira kwemuviri.
Chii chinonzi Applications OfSulforaphane?
DETARY SUPPLEMENTS:
1.Antioxidant supplements: Sulforaphane inowanzoshandiswa mu antioxidant supplement kuti ibatsire kuderedza mahara radicals uye kuderedza kukuvara kweoxidative stress kumuviri.
2.Anti-cancer supplement: Inoshandiswa mumishonga inopesana nekenza kubatsira kudzivirira kukura uye kuwanda kwemasero emukenza uye kuwedzera simba rekudzivirira kenza.
CHIDYA CHINOSHANDA:
1.KUDYA ZVINONYANYA: Sulforaphane inogona kuwedzerwa kune zvinoshanda zvekudya zvakadai sezvinwiwa zvehutano uye mabhawa ekudya kuti ape humwe hutano hunobatsira.
2.Vegetable Extract: Sechidimbu chemiriwo yecruciferous, inoshandiswa zvakanyanya muzvokudya zvakasiyana-siyana zvehutano.
ZVINHU ZVINOGONESA ZVINHU:
1.Antioxidant skin care products: Sulforaphane inoshandiswa mu antioxidant skin care products kuti ibatsire kuderedza mahara radicals uye kuderedza oxidative kukuvara kweganda.
2.Anti-inflammatory skin care products: Inoshandiswa mu-anti-inflammatory skin care products kuti ibatsire kuderedza kupisa kweganda uye kuchengetedza hutano hweganda.
Inoenderana Mibvunzo Unogona Kufarira:
Ndeapi maside effects esulforaphane?
Sulforaphane inzvimbo inongoitika organosulfur inowanikwa kunyanya mumiriwo yecruciferous senge broccoli, cauliflower, kale, uye masitadhi miriwo. Kunyangwe Sulforaphane ine akawanda mabhenefiti ehutano, mune dzimwe nguva, mamwe maside mhedzisiro anogona kuitika. Izvi zvinotevera zvinogona kuitika uye ekudzivirira kweSulforaphane:
1. Kusagadzikana kwemudumbu:
- Bloating uye Gasi: Vamwe vanhu vanogona kuona zviratidzo zvekuputika uye gasi mushure mekutora madosi akakwira eSulforaphane.
- Diarrhea: Kukwirisa madhasi eSulforaphane kunogona kukonzera manyoka, kunyanya muvanhu vane hanya.
- Marwadzo Emudumbu uye Nausea: Vamwe vanhu vanogona kunzwa kurwadziwa kwemudumbu uye kusvotwa mushure mekudya Sulforaphane.
2. Allergic Reaction:
- Kuita kweGanda: Nhamba diki yevanhu inogona kunge iine allergic reaction kuSulforaphane, ichiratidza seyakafunuka, kuputika kutsvuka, kana mikoko.
-Kunetseka kufema: Kashoma, Sulforaphane inogona kukonzera allergic reaction, sekunetseka kufema kana kuzvimba kwehuro. Kana zviratidzo izvi zvikaitika, tsvaga kurapwa nekukurumidza.
3. Kukanganisa kushanda kwethyroid:
- Goiter: Cruciferous miriwo ine zvimwe zvakasikwa thyroid-inhibiting zvinhu (senge thiocyanates). Kutora kwenguva refu kwehuwandu hwakawanda kunogona kukanganisa thyroid basa uye kutungamirira mukuwedzerwa kwetroroid (goiter).
- Hypothyroidism: Muzviitiko zvisingawanzoitiki, kwenguva refu, kudya kwakanyanya kweSulforaphane kunogona kukanganisa thyroid hormone synthesis, zvichiita kuti hypothyroidism.
4. Kudyidzana kwezvinodhaka:
- Anticoagulants: Sulforaphane inogona kukanganisa kushanda kweanticoagulants (senge warfarin) uye kuwedzera njodzi yekubuda ropa.
- Mimwe Mishonga: Sulforaphane inogona kupindirana nemamwe madhiragi, ichikanganisa metabolism uye kushanda kwayo. Kana uchitora Sulforaphane uchitora mishonga, unofanirwa kubvunza chiremba wako.
Notes:
1. Kudya zvine mwero:
- Kudzora Dose: kunyangweSulforaphaneine zvakawanda zvinobatsira zvehutano, inofanira kutorwa zvine mwero kudzivirira kuwandisa. Zvinowanzo kurudzirwa kuwana Sulforaphane kuburikidza nekushandisa miriwo yecruciferous pane kuvimba nepamusoro-dose yekuwedzera.
2. Kusiyana kwevanhu:
-Sensitive People: Vamwe vanhu vanogona kunge vakanyanya kunzwira kuSulforaphane uye vanowanzoita mhedzisiro. Iri boka revanhu rinofanira kubhadhara zvakanyanya pakutora kwavo uye kugadzirisa panguva yakakodzera kana kusagadzikana kuchiitika.
3. Vakadzi vane pamuviri uye vanoyamwisa:
- SHANDISA NECHENJERERA: Vakadzi vane pamuviri uye vanoyamwisa vanofanira kungwarira pavanenge vachinwisa Sulforaphane, zviri nani pasi pekutungamirirwa nachiremba.
4. Varwere vane zvirwere zvisingaperi:
- ONANA NACHIREMBA: Varwere vane zvirwere zvisingaperi (zvakadai sechirwere chetachiona, chirwere chechiropa, kana chirwere chetsvo) vanofanira kubvunza chiremba vasati vatora Sulforaphane kuti vave nechokwadi chekuchengeteka.
Ndinogona kutora nguva yakareba sei sulforaphane?
Kudya Kwekudya: Yakachengeteka kushandiswa kwenguva refu sechikamu chekudya kwakadzikama kwakapfuma mumiriwo yecruciferous.
Supplemental Intake: Kazhinji yakachengeteka kushandiswa kwenguva pfupi; kushandiswa kwenguva refu kunofanira kutungamirirwa nenyanzvi yehutano.
Zvinoita cancersulforaphanekudzivirira?
Sulforaphane ine huwandu hwakawanda hweaanti-gomarara zvivakwa uye inogona kudzivirira uye kuvharidzira mhando dzakawanda dzegomarara, kusanganisira zamu, prostate, colon, mapapu, dumbu, dundira uye gomarara reganda. Nzira dzayo huru dzinosanganisira kudzivisa kukura uye kupararira kwemasero emukenza, kukonzera apoptosis, inhibiting tumor angiogenesis, antioxidant, anti-inflammatory uye detoxification, etc. Nokudya sulforaphane-rich cruciferous miriwo, njodzi yemhando dzakawanda dzekenza inogona kunyatsoderedzwa.
Ko sulforaphane inowedzera estrogen here?
Tsvagiridzo yazvino inoratidza kuti Sulforaphane inogona kukanganisa metabolism uye mhedzisiro yeestrogen kuburikidza nemaitiro akawanda, kusanganisira kusimudzira estrogen detoxification, modulating estrogen metabolic nzira, inhibiting estrogen receptors, uye kuderedza estrogen kusaina.
Nguva yekutumira: Sep-19-2024